Buffs
Accuracy
After Image
Amplify
Battle Hymn
Berserk
Blasphemer
Blur
Brutality
Burst
Collect
Combust
Corruption
Creative AI
Dark Embrace
Demon Form
Deva
Devotion
Double Damage
Double Tap
Duplication
Echo Form
Electro
Envenom
Equilibrium
Establishment
Evolve
Feel No Pain
Fire Breathing
Flame Barrier
Foresight
Free Attack Power
Heatsink
Hello
Infinite Blades
Juggernaut
Like Water
Loop
Machine Learning
Magnetism
Master Reality
Mayhem
Mental Fortress
Nightmare
Nirvana
Noxious Fumes
Omega
Panache
Pen Nib
Phantasmal
Rage
Rebound
Regeneration
Rushdown
Repair
Rupture
Sadistic
Simmering Rage
Static Discharge
Storm
Study
Surrounded
The Bomb
Thousand Cuts
Tools of the Trade
Wave of the Hand
Well-Laid Plans
Angry
Back Attack
Beat of Death
Curiosity
Curl Up
Enrage
Explosive
Fading
Invincible
Life Link
Malleable
Minion
Mode Shift
Painful Stabs
Reactive
Sharp Hide
Shifting
Split
Spore Cloud
Stasis
Strength Up
Thievery
Time Warp
Unawakened
Artifact
Barricade
Buffer
Dexterity
Draw Card
Energized
Focus
Intangible
Mantra
Metallicize
Next Turn Block
Plated Armor
Regenerate
Ritual
Strength
Thorns
Vigor
Understanding buffs in Slay the Spire
Buffs increase your damage, defense, or resource generation. Core examples include Strength, Dexterity, and Focus. Building around permanent or repeatable buffs is a proven way to stabilize elite and boss fights. Browse each buff to learn how it stacks, its common sources, and best pairings.